Schizophrenia in Offspring of Holocaust Survivors: Intergenerational Effects of Preconception Parental Trauma Within the Jerusalem Perinatal Study

The authors aimed to investigate whether parental preconception trauma, specifically from Holocaust experiences, increases the risk of schizophrenia in their offspring. Their findings indicate that children of mothers who were older than five years at the time of the trauma have more than double the risk of developing schizophrenia, highlighting the significance of the timing of trauma exposure in the intergenerational transmission of psychiatric disorders.