May 7, 2026 · BMC women's health · DOI: 10.1186/s12905-026-04516-w

Effects of gallic acid on cyclophosphamide-induced experimental ovarian injury in rats

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This study investigates the protective effects of gallic acid (GA) against ovarian damage induced by cyclophosphamide (CP) in rats, addressing concerns about chemotherapy's impact on reproductive health. The results indicate that GA significantly reduces follicular cell degeneration and improves ovarian function compared to CP treatment alone, suggesting its potential as a prophylactic agent in preserving ovarian health during chemotherapy.

Elif Koyun Alvuroğlu, Derya Öztürk Okatan, Elif Şahin, Ahmet Alver

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