Imaging Biomarkers for Early Differentiation of Candida and Aspergillus Endogenous Fungal Endophthalmitis: Multicenter Optical Coherence Tomography-Based Analysis
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The study aimed to differentiate between Candida and Aspergillus species in cases of endogenous fungal endophthalmitis (EFE) associated with retinochoroiditis by analyzing clinical characteristics and optical coherence tomography (OCT) findings. The authors found distinct morphological and OCT features that could reliably distinguish the two fungal etiologies, achieving approximately 85% accuracy in species differentiation using machine-learning classification. These findings suggest that OCT-based biomarkers can aid in early, organism-specific management of EFE while awaiting microbiological confirmation.
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