April 30, 2026 · Obstetrics and gynecology · DOI: 10.1097/AOG.0000000000006296

Self-Sampling for Cervical Cancer Screening in Transmasculine and Nonbinary People

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This narrative review investigates the potential of high-risk HPV self-sampling as a cervical cancer screening method for transmasculine and nonbinary individuals, who are often underserved in traditional screening practices. The findings indicate that self-sampling is widely accepted and preferred over clinician-collected samples, leading to increased adherence to screening. The authors emphasize the need for further research to refine follow-up recommendations and assess the long-term impact of self-sampling on screening adherence in these populations.

Madelyn Clark, Jack Rusley, Chelsea Graham, Beth Cronin

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