April 20, 2026 · The American journal of sports medicine · DOI: 10.1177/03635465261438145

Progressive Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction: Longitudinal Evidence From the Swedish Knee Ligament Registry

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This study aimed to evaluate the progression of cartilage damage in patients undergoing anterior cruciate ligament reconstruction (ACLR) by comparing findings from primary and revision surgeries. The results indicated a significant increase in the prevalence, size, and severity of cartilage lesions over time, with older age, pre-existing meniscal and cartilage injuries, and longer intervals between injury and revision surgery identified as key risk factors for cartilage degeneration. These findings highlight the need for improved strategies to address posttraumatic joint deterioration following ACL injuries.

Piero Agostinone, Iacopo Romandini, Pierre Rotzius, Stefano Zaffagnini, Magnus Forssblad, Alexander Sandon

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