Statistical Robustness of Randomized Controlled Trials Comparing Biceps Tenotomy Versus Tenodesis: A Reverse Continuous Fragility Index Analysis

The authors aimed to assess the statistical robustness of nonsignificant outcomes in high-quality randomized controlled trials comparing biceps tenotomy and tenodesis during shoulder arthroscopy. Their analysis, using the reverse continuous fragility index (rCFI), revealed that while the studies generally indicated noninferiority in clinical outcomes, a significant portion of the nonsignificant results could be reconsidered as significant, suggesting moderate robustness in the findings. Overall, the study highlights the importance of evaluating statistical fragility in interpreting clinical trial results.