Lidocaine combined with low-dose esketamine for movement-evoked pain after hepatectomy: a double-blind randomised controlled trial
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The authors aimed to determine whether the combination of lidocaine and low-dose esketamine could effectively reduce movement-evoked pain, decrease opioid consumption, and enhance recovery quality in patients undergoing hepatectomy. The study found that this combination significantly lowered pain scores and opioid use in the first 72 hours post-surgery, although the clinical significance of these findings was considered modest.
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