The Synovial Fingerprint of Ankle Fractures: A Central Role for WNT Pathway Activation in Posttraumatic Ankle Osteoarthritis
Listen to this summary
This study investigates the molecular mechanisms linking ankle fractures to the development of posttraumatic osteoarthritis (PTOA) by analyzing synovial tissue transcriptional changes. The authors identify distinct synovial gene expression profiles associated with PTOA, highlighting the central role of WNT pathway activation in the disease process. Their findings suggest that understanding these molecular drivers could inform early therapeutic interventions following ankle fractures.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Foot & ankle international
View all →Mar 24, 2026 · Foot & ankle international
Multiplanar Interactions in the Cavovarus Foot
Mar 20, 2026 · Foot & ankle international
Impact of Non-Tobacco Nicotine Use on Outcomes Following Total Ankle Arthroplasty
Mar 17, 2026 · Foot & ankle international
Peroneal Artery Danger Zone With Syndesmotic Screw Fixation: A Computed Tomography Angiography Study
Mar 17, 2026 · Foot & ankle international
Total Ankle Arthroplasty vs Arthrodesis in an HbA<sub>1c</sub>-Defined Diabetic Cohort: Lower 1- to 5-Year Structural Complication Rates in a Retrospective Propensity-Matched Study
Mar 17, 2026 · Foot & ankle international
Does Platelet-Rich Plasma Speed Recovery After Acute Lateral Ankle Sprain? A Prospective Comparative Study Among Athletes
Mar 17, 2026 · Foot & ankle international
Medial Malleolar Osteotomy: The Influence of 2 Types of Osteotomies and 2 Fixation Methods on Articular Displacement in Fresh-Frozen Cadaveric Specimens
More in Orthopaedic Surgery
View all →Mar 25, 2026 · The American journal of sports medicine
Clinical Outcomes of Unipolar Versus Bipolar Patellofemoral Fresh Osteochondral Allograft Transplantation
Mar 25, 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Editorial Commentary: Early Changes, Lasting Gains: Ten-Year Outcomes After Hip Arthroscopy For Tönnis 0 and 1
Mar 25, 2026 · The American journal of sports medicine
Deltoid Osteomuscular Transfer Suppresses Humeral Head Translation Caused by Massive Irreparable Rotator Cuff Tears: A Cadaveric Biomechanical Study
Mar 25, 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Editorial Commentary: Anxiety and Depression May Be More Important Than the Alpha Angle or Suction Seal in Hip Preservation Surgery Outcomes
Mar 25, 2026 · British journal of sports medicine
Injury risk and its relationship with biological maturation among 100 junior tennis athletes: a 15-year retrospective analysis
Mar 25, 2026 · The American journal of sports medicine
Tibiofemoral Load Sharing and Lateral Meniscal Function Are Restored in Tibia- and Capsular-Based Repair of Type 3 Lateral Meniscal Oblique Radial Tears
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
