March 20, 2026 · Obstetrics and gynecology · DOI: 10.1097/AOG.0000000000006245

Intravenous Ferumoxytol Compared With Oral Ferrous Sulfate for Iron Deficiency Anemia in Pregnancy: A Randomized Controlled Trial

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The authors aimed to compare the effectiveness of intravenous (IV) ferumoxytol versus oral ferrous sulfate in increasing hemoglobin levels for treating iron deficiency anemia (IDA) during pregnancy. Their randomized controlled trial found that IV ferumoxytol significantly improved hemoglobin levels at 4 and 8 weeks, resolved anemia more effectively, and resulted in higher postpartum hemoglobin compared to oral ferrous sulfate.

Irogue Igbinosa, Stephanie A Leonard, Ijeoma Iwekaogwu, Elizabeth B Sherwin, Caroline Berube, Deirdre J Lyell

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