HIV-Associated Complications: A Systems-Based Approach

The authors investigate the ongoing complications associated with HIV in the era of effective antiretroviral therapy, despite improved life expectancy for those living with the virus. They highlight the prevalence of various comorbidities, including cardiometabolic issues, neurocognitive impairments, and chronic kidney disease, while emphasizing the importance of primary care clinicians in managing these complications through routine screening and lifestyle interventions. The paper underscores the need for a comprehensive, systems-based approach to address the multifaceted health challenges faced by individuals with HIV.