September 15, 2026 · British journal of anaesthesia · DOI: 10.1016/j.bja.2026.07.004

Turning over new stones and discovering new questions in the contributions of anaesthetic drugs to perioperative cardiac arrest

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The authors explore the contributions of various anaesthetic drugs to the risk of perioperative cardiac arrest by utilizing data from the WHO VigiBase registry. They highlight the establishment of a Risk of Reporting (RoR) metric, which compares the incidence of cardiac arrest linked to specific anaesthetic agents against their usage, with propofol as a reference. This metric aims to guide future research on the relationship between anaesthetic medications and perioperative cardiac arrest risk.

Michael F O'Connor, Richard P Dutton

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