September 11, 2026 · Archives of disease in childhood · DOI: 10.1136/archdischild-2026-331272

Evolving landscape of paediatric sepsis: progress, gaps and the next generation of tools

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The authors examine the evolving landscape of paediatric sepsis, aiming to identify progress made in its management and the persistent gaps that contribute to childhood mortality. They highlight advancements such as the Phoenix Sepsis Criteria and vaccination programs, while also addressing challenges in early recognition and treatment stratification. The paper suggests that future improvements may hinge on risk stratification and the application of machine learning for better early detection, necessitating further validation before implementation.

Pamela Jump Salcedo, Daniel R Owens

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