September 8, 2026 · Archives of disease in childhood · DOI: 10.1136/archdischild-2026-330907

Quality and concordance of international paediatric sepsis guidelines: a cross-sectional appraisal from the SENTINEL International study

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The authors aimed to evaluate the methodological quality of hospital-specific pediatric sepsis clinical practice guidelines (CPGs) and assess their consistency and concordance with the Surviving Sepsis Campaign 2020 standards. Their findings revealed that all 14 CPGs assessed were of low methodological quality, yet most aligned with key time-critical recommendations from SSC 2020, highlighting significant variations in fluid resuscitation and steroid administration practices.

Tom Solan, Amanda Williams, Shane George, Adin Breuer, Stephen Hearps, Adriana Yock-Corrales, Viviana Pavlicich, Kandamaran Krishnamurthy, Yashica Seymour-Hanna, Radhika Raman, Bharat Choudhary, Weda Kusuma, Victoria Ribaya, Nathan Forsyth, Nilanka Mudithakumara, Nichkamol Lertamornkitti, Antionette David, Suleiman Mohamed, Tigist Bacha, Jenala Njirammadzi-Maleta, John Appiah, Janvier Hitayezu, Mukami Kunga, Genevieve Po Gee Fung, Rahimi Abdrazak, Shu-Ling Chong, Jhong-Lin Wu, Jeong-Yong Lee, Damian Roland, Bressan Silvia, Ruth Logan, Yolanda Ballestero, Ozlem Teksam, Lina Jankauskaite, Graham Thompson, Vikram Sabhaney, Yasaman Shayan, Elysha Pifko, Julia Lloyd, Khalid Al Ansari, Franz E Babl, Elliot Long

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Sep 23, 2026 · The New England journal of medicine

Dr. Jennifer Thompson

Portland, OR

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Quality and concordance of international paediatric sepsis guidelines: a cross-sectional appraisal from the SENTINEL International study

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