Systematic review and meta-analysis of intrathecal drug delivery systems for the treatment of chronic refractory non-cancer pain
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The authors aimed to evaluate the clinical outcomes and safety of intrathecal drug delivery (ITDD) systems for treating chronic non-cancer pain. Their systematic review and meta-analysis of 39 studies found a significant mean reduction in pain intensity, along with improvements in function and health-related quality of life; however, the evidence quality was low due to study limitations, highlighting the need for better reporting and controlled trials.
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