Time-dependent diffusion MRI for assessing tumor microstructure and prognostic risk factors in cervical cancer

The authors aimed to assess the utility of time-dependent diffusion MRI (td-dMRI) in noninvasively characterizing tumor microstructure and predicting prognostic risk factors in cervical cancer. Their findings indicate that specific td-dMRI parameters, particularly the intracellular water exchange time and certain diffusion coefficients, may serve as potential imaging biomarkers for differentiating tumor types and assessing histological grade and lymphovascular space invasion. However, the authors emphasize the need for further validation in larger, multicenter studies.