July 31, 2026 · Obstetrics and gynecology · DOI: 10.1097/AOG.0000000000006378

Evaluating Routine Opioid Compared With Nonopioid Prescribing After Laparoscopic Hysterectomy: A Randomized Controlled Trial

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The authors aimed to determine whether a nonopioid postoperative pain regimen is noninferior to routine opioid prescribing in terms of pain scores and patient satisfaction after laparoscopic hysterectomy for benign conditions. The study found that pain scores were similar between the nonopioid and opioid groups, and satisfaction with pain control was high in both, indicating that nonopioid management is a viable alternative that also significantly reduces opioid consumption.

Marie-Claire Leaf, Julia Wainger, Anja Frost, Kelsey Musselman, Kristin Patzkowsky, Khara Simpson, Harold Wu, Dhananjay Vaidya, Jianqiao Ma, Abdelrahman AlAshqar, Karen C Wang, Mostafa A Borahay

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