STAGE II NON-SMALL CELL LUNG CANCER: UPFRONT SURGERY OR NEOADJUVANT CHEMOIMMUNOTHERAPY
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The authors investigate whether neoadjuvant chemoimmunotherapy offers better overall survival compared to upfront surgery in stage-II non-small cell lung cancer patients. Their analysis reveals that while neoadjuvant chemoimmunotherapy improves survival compared to surgery in the 8th edition TNM database, results are similar in the 9th edition. Additionally, chemoimmunotherapy shows superior pathological response rates and event-free survival compared to chemotherapy, although surgical outcomes remain comparable.
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