May 26, 2026 · JAAPA : official journal of the American Academy of Physician Assistants · DOI: 10.1097/01.JAA.0000000000000361

Lipoprotein(a) screening: Balancing benefits and challenges in clinical decision-making

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This article addresses the question of how to effectively implement lipoprotein(a) (Lp(a)) screening in clinical practice, given its association with increased risk of atherosclerotic cardiovascular disease (ASCVD) independent of traditional risk factors. The author reviews the biochemistry, clinical significance, and management options for elevated Lp(a) levels, highlighting the potential benefits and challenges of integrating Lp(a) testing into routine healthcare to better identify individuals at elevated cardiovascular risk.

Nolan Crain

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