June 9, 2026 · Spine · DOI: 10.1097/BRS.0000000000005759

Epinephrine-added Irrigation Shortens and Stabilizes Operative Time in Full-endoscopic Lumbar Decompression after Adjusting for the Learning Curve: An Interrupted Time Series Study

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The authors aimed to determine whether epinephrine-added irrigation enhances operative efficiency and visualization during full-endoscopic lumbar decompression while accounting for the learning curve. Their study found that using epinephrine significantly reduced mean operative time and improved visibility, with a notable decrease in the need for hemostasis, all without causing significant hemodynamic instability. This suggests that epinephrine-added irrigation is beneficial in this surgical context.

Shota Takenaka, Sadaaki Kanayama, Shutaro Yamada, Tsuyoshi Kono

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