March 26, 2026 · Journal of medical toxicology : official journal of the American College of Medical Toxicology · DOI: 10.1007/s13181-026-01135-7

n-Hexane-Toxic Neuropathy Presenting with Cauda Equina Inflammation

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This case study investigates the occurrence of n-hexane-toxic neuropathy presenting with cauda equina inflammation, a condition not previously reported. The authors highlight the importance of considering n-hexane exposure in patients with polyneuropathy and cauda equina symptoms, suggesting that sural nerve biopsy may be a useful diagnostic tool in such cases. The patient's recovery following intravenous immunoglobulin therapy underscores the potential for improvement with appropriate treatment.

Rika Nohara, Hiroya Kuwahara, Honami Kawai, Tatsuhiko Sano, Kinya Ishikawa, Takashi Kanda, Yoichiro Nishida

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