Role of Angiotensin II as a Vasoactive Agent to Treat Distributive Shock With a Focus on Preliminary Data in Pediatric-Aged Patients

This review investigates the role of angiotensin II (AT-II) as a vasoactive agent in treating distributive shock, particularly in pediatric patients, where conventional treatments may be insufficient. The authors highlight existing evidence suggesting AT-II can improve mean arterial pressure in both adults and children, but note the lack of robust data on long-term survival outcomes. They call for future research to better define the dosing strategies and potential survival benefits of AT-II in this context.