Cognitive and behavioural skills to prevent major depression among adults with subthreshold depression: 50-week follow-up analysis of smartphone CBT randomised trials (RESiLIENT trial)

The authors aimed to evaluate the long-term effects of smartphone-delivered cognitive behavioral therapy (CBT) skills on preventing major depression and reducing the total burden of depression in adults with subthreshold depression over a 50-week period. The study found that specific combinations of CBT skills, particularly behavioral activation with assertion training and cognitive restructuring, significantly reduced the onset of major depression and overall depressive symptoms. These results suggest that smartphone-based CBT is a promising and accessible preventive intervention for at-risk individuals.