April 23, 2026 · Prenatal diagnosis · DOI: 10.1002/pd.70157

Novel Fetal Embolization Technique via Transcardiac Transarterial Ultrasound- and Fluoroscopy-Guided Endovascular Surgery for Vein of Galen Malformation: Preclinical Study in the Fetal Lamb

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The authors aimed to evaluate the feasibility and safety of a novel prenatal transarterial embolization technique, termed FETTUS, for treating vein of Galen malformation in a preclinical model using fetal lambs. The study demonstrated successful embolization in a majority of cases, with no adverse effects observed, suggesting that FETTUS could be a viable therapeutic option for this condition in humans.

Emma Van den Eede, Karen Chen, Carolyn Altman, Tomohiro Arai, Wasinee Tianthong, Walter Coudyzer, Greetje Vande Velde, Michael Aertsen, Timo Krings, Peter Kan, Caitlin Sutton, Samuel McCluggage, William E Whitehead, Magdalena Sanz Cortes, Larry H Hollier, Luc De Catte, Thierry A G M Huisman, Michael A Belfort, Jan Deprest, Luc Joyeux

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