March 22, 2026 · Prenatal diagnosis · DOI: 10.1002/pd.70125

Twin Reversed Arterial Perfusion (TRAP) Sequence: Proposal for Morphologic Classification System Predicting Natural History

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The authors aimed to establish a new morphological classification system for Twin Reversed Arterial Perfusion (TRAP) sequence based on skeletal characteristics and to evaluate its prognostic implications for expectantly managed cases. They identified five morphological types and found significant differences in survival rates among these types, with better outcomes associated with acardiac twins exhibiting minimal structural development. This classification may enhance prenatal counseling for TRAP cases.

Li Lu, Li Li, Quan Gan, Chen Cheng, Sheng Zhao, Xiao-Hong Yang

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