A comparison of high dose versus low dose intranasal midazolam for sedation in the pediatric emergency department
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The authors aimed to compare the efficacy of high-dose versus low-dose intranasal midazolam for sedation in pediatric emergency department patients, specifically assessing the need for additional rescue sedation medications. Their findings indicated that patients receiving high-dose midazolam (0.5 mg/kg) required fewer additional sedatives compared to those receiving low-dose midazolam (0.2 mg/kg), without increasing adverse events or length of stay in the emergency department.
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