Medical Therapy for NF2-related Schwannomatosis: A Systematic Review of Current Evidence
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The authors aim to synthesize the existing evidence on medical therapies for managing NF2-related vestibular schwannomas. Their systematic review reveals that bevacizumab shows the most consistent efficacy in improving hearing and controlling tumors, while other therapies like mTOR inhibitors and tyrosine kinase inhibitors exhibit variable outcomes. The authors emphasize the need for high-quality, prospective randomized controlled trials to better understand the efficacy and comparative effectiveness of these treatments.
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