HBsAg seroclearance further reduces hepatocellular carcinoma but not hepatic decompensation in patients with cirrhosis and complete viral suppression
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The authors aimed to determine whether HBsAg seroclearance offers additional clinical benefits over complete viral suppression in patients with chronic hepatitis B and cirrhosis. Their findings indicate that while HBsAg seroclearance significantly reduces the risk of hepatocellular carcinoma (HCC), it does not affect the risk of hepatic decompensation compared to patients with only complete viral suppression.
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