June 3, 2026 · Journal of palliative medicine · DOI: 10.1177/10966218261455968

Early Palliative Care for People with Primary Malignant Brain Tumors: A Systematic Review

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This systematic review investigates the role and timing of early palliative care (ePC) in patients with primary malignant brain tumors (PMBT) to determine its impact on quality of life and healthcare outcomes. The authors found that ePC is infrequently implemented, with varying definitions of "early," but it may lead to reduced aggressive end-of-life care and improved patient outcomes. They call for prospective trials to better define ePC's effects on quality of life, survival, and healthcare utilization in this population.

Jennifer C Hall, Connor Barrett, Soren Christensen, Juliet Dalton, Samantha Kaplan, Christopher A Jones, Margaret O Johnson

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